Ecosystem

Connecting Academic Discovery, Platform R&D & Global Commercialisation

Breakthrough genetic medicine development requires cross-functional collaboration between academic labs, research funding bodies, dedicated technology innovators and global commercialisation partners. Branca Bunús leads a complete interconnected ecosystem built entirely around our proprietary HPAE delivery platform.

Core structure

Ecosystem core structure

The entire HPAE innovation value chain originates from UCD academic research, is advanced exclusively by Branca Bunús for therapeutic pipeline and polymer platform innovation, with all reagent product global market activity delegated to strategic partner PolyGene Biotech under exclusive commercial licensing terms. The ecosystem is supported by Irish national innovation funding bodies Enterprise Ireland and Research Ireland.

01

UCD academic research

02

BrB platform & therapeutics

03

PolyGene global commercialisation

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Irish national innovation support

Professor Wenxin Wang and Dr Hongyun Tai receiving the NovaUCD Innovation Award
Prof Wang and Dr Tai at the NovaUCD Innovation Award — recognition from the Irish innovation ecosystem.
Partnership model

One Shared HPAE Vision, Two Complementary Strategic Focuses

Branca Bunús logo

Branca Bunús Ltd

  • HPAE platform IP ownership and core polymer R&D
  • Pre-clinical in-vivo gene medicine pipeline development (BRB101 / BRB202)
  • Academic and therapeutic licensing collaboration
PolyGene Bio logo

PolyGene Biotech

  • Exclusive global transfection reagent manufacturing and distribution
  • BrPERfect / TransPi product technical customer support
  • Reagent formulation iterative optimisation for biomanufacturing workflows

Independent legal entities, shared founding core team, aligned long-term HPAE platform growth goals.

Strategic partnership

Branca Bunús Ltd and PolyGene Biotech operate as independent entities under a long-term strategic partnership, founded by the HPAE technology inventor Professor Wenxin Wang. BrB retains the ownership of HPAE platform intellectual property and leads therapeutic pipeline development; PolyGene holds exclusive global manufacturing, distribution and commercialisation rights for all transfection reagent lines.

In the field

Conferences and community

From international conferences to the DEB community, we bring the HPAE platform to the people it serves.

Branca Bunús and PolyGene teams at ISCT 2026 in Dublin
Prof Wang, Dr Tai and the teams from Branca Bunús and PolyGene presented at International Society for Cell and Gene Therapy (ISCT) 2026 in Dublin.
Branca Bunús and PolyGene teams at CPIC 2026 in Shanghai
Prof Wang, Dr Tai and the teams from Branca Bunús and PolyGene presented at 1st China Pharmaceutical Innovation Conference (CPIC 2026) in Shanghai.
DEBRA group photograph outdoors.
DEBRA and the EB community.
Sister company

Our sister company Blafar Ltd

Blafar Ltd shares our founding scientific roots and complements the Branca Bunús ecosystem with specialist chemistry and materials expertise.

Blafar Ltd team in the laboratory.
The team at our sister company, Blafar Ltd.

Academic research partner: University College Dublin

Long-standing continuous collaboration with Professor Wenxin Wang’s UCD Charles Institute lab, including joint I-Form Centre polymer research programmes and industry PhD training initiatives funded by Research Ireland to advance next-generation HPAE polymer variants.

Irish national innovation support

As an Enterprise Ireland High Potential Start-Up, Branca Bunús receives structured government innovation support for international expansion, R&D project funding and market validation via Research Ireland and Enterprise Ireland collaborative research grants.

Ecosystem expansion roadmap

We continuously expand our global partner network including academic institutions, biotech startups, large pharma groups, clinical trial organisations and global reagent distribution partners to unlock the full HPAE platform potential.

University College Dublin logoUniversity College Dublin
I-Form Advanced Manufacturing Research Centre logoI-Form Advanced Manufacturing Research Centre
Enterprise Ireland logoEnterprise Ireland
Research Ireland logoResearch Ireland

Build Collaborative Partnerships With Our Ecosystem